THE EFFECT OF ORAL GLUCOSE ON VON WILLEBRAND FACTOR ACTIVITY IN NORMAL AND DIABETIC SUBJECTS
- 1 June 1977
- journal article
- research article
- Published by Wiley in Clinical Endocrinology
- Vol. 6 (6) , 437-442
- https://doi.org/10.1111/j.1365-2265.1977.tb03326.x
Abstract
Increased platelet aggregation and high von Willebrand factor activity was noted in patients with chemical diabetes. Platelet aggregation, plasma glucose, insulin, free fatty acids, growth hormone and von Willebrand factor activity were studied during the glucose tolerance test in 6 normal and 6 chemical diabetic subjects. von Willebrand factor activity is probably suppressed coincident with the rise of glucose and insulin. Evidence of hormonal and metabolic control of levels of von Willebrand factor activity was provided.This publication has 9 references indexed in Scilit:
- Von Willebrand factor activity in normal subjects: Sex difference and variabilityThrombosis Research, 1975
- Platelet hyperaggregation and increased plasma level of von Willebrand factor in diabetics with retinopathyDiabetologia, 1975
- Increased Platelet Aggregation in Early Diabetus MellitusAnnals of Internal Medicine, 1975
- INCREASED VON WILLEBRAND‐ANTIHAEMOPHILIC FACTOR A IN DIABETIC RETINOPATHYActa Ophthalmologica, 1974
- Nature of von Willebrand Factor: A New Assay and a Specific InhibitorProceedings of the National Academy of Sciences, 1974
- Immunological Characterization of Purified Anti-Haemophilic Factor A (Factor VIII) which corrects Abnormal Platelet Retention in Von Willebrand's DiseaseNature New Biology, 1972
- Platelet adhesiveness and aggregation in relation to diabetic retinopathyDiabetologia, 1971
- Immunoassay of Insulin: Two Antibody System: Plasma Insulin Levels of Normal, Subdiabetic and Diabetic RatsDiabetes, 1963