TRISOMY-8 IN ACUTE MYELOID-LEUKEMIA - NONRANDOM EVENT - LACK OF CORRELATION WITH PROGNOSIS AND CYTOKINETIC PARAMETERS

  • 1 January 1977
    • journal article
    • research article
    • Vol. 18  (2) , 163-169
Abstract
Six cases of AML [acute myeloid leukemia] with a supernumerary chromosome 8 as the only aberration in practically all bone marrow mitoses and 10 cases with a normal chromosome composition of the marrow cells were investigated to evaluate the possible influence of trisomy 8 on some clinical and cytokinetic parameters. No significant differences between the groups were found. A supernumerary chromosome 8 was present in 36% of AML patients with chromosomal aberrations.

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