A Convenient Method for the Preparation of Ketones by the Reaction of Grignard Reagents with Carboxylic Acid Derivatives
- 1 July 1974
- journal article
- research article
- Published by Oxford University Press (OUP) in Bulletin of the Chemical Society of Japan
- Vol. 47 (7) , 1777-1780
- https://doi.org/10.1246/bcsj.47.1777
Abstract
It was found that ketones were prepared in excellent yields by the reaction of Grignard reagents with S-(2-pyridyl) thioates and their analogues or with 2-pyridyl esters. The mechanism of this reaction was also discussed. This useful method for the preparation of ketones was successfully applied to the syntheses of cis-jasmone and dihydrojasmone.Keywords
This publication has 8 references indexed in Scilit:
- Reaction of S-(2-pyridyl) thioates with Grignard reagents. Convenient method for the preparation of ketonesJournal of the American Chemical Society, 1973
- Dihydro-1,3-oxazines. XVI. General synthesis of 2-alkylcyclopentenones and a method for adding CH2CO2Me to electrophilic olefins. Application to the synthesis of methyl jasmonateThe Journal of Organic Chemistry, 1973
- A Convenient Method for Hydrolysis of 1,3-Dithiane Derivatives Using Cupric ChlorideBulletin of the Chemical Society of Japan, 1972
- Synthesis of ketones from dihydro-1,3-oxazines via stepwise alkyl or aryl introductionThe Journal of Organic Chemistry, 1972
- The Reaction of Trialkylboron and α-Lithiobenzyl-2-pyridyl or Phenylsulfide. A Convenient Method for the Preparation of AlkylbenzenesBulletin of the Chemical Society of Japan, 1972
- A Useful Method for Reductive Fission of Sulfides and Its Application to Carbon-Carbon Bond FormationBulletin of the Chemical Society of Japan, 1971
- A Convenient Method for the Preparation of ThiolestersBulletin of the Chemical Society of Japan, 1970
- Über das Verhalten der γ‐Diketone, III. Mitteil.: Die Synthese des JasmonsBerichte der deutschen chemischen Gesellschaft (A and B Series), 1942