Different modes of action of inhibitors of bacterial D-amino acid transaminase. A target enzyme for the design of new antibacterial agents.
Open Access
- 1 May 1981
- journal article
- research article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 256 (9) , 4263-4268
- https://doi.org/10.1016/s0021-9258(19)69428-7
Abstract
No abstract availableThis publication has 35 references indexed in Scilit:
- β-Elimination of β-halo substrates by D-amino acid transaminase associated with inactivation of the enzyme. Trapping of a key intermediate in the reactionBiochemistry, 1978
- Suicide substrates for the alanine racemase of Escherichia coli BBiochemistry, 1978
- Synthesis and resolution of 3-fluoro-D,L-alanine-2-d: a selective deuteration via reductive amination with sodium borodeuterideThe Journal of Organic Chemistry, 1978
- The in vivo inhibition of gaba-transaminase by gabaculineBiochemical and Biophysical Research Communications, 1977
- Isolation and inhibitory activity of gabaculine, a new potent inhibitor of γ‐aminobutyrate aminotransferase produced by a StreptomycesFEBS Letters, 1977
- The irreversible inhibition of mouse brain .gamma.-aminobutyric acid (GABA)-.alpha.-ketoglutaric acid transaminase by gabaculineJournal of the American Chemical Society, 1976
- Organofluorine synthesis via photofluorination: 3-fluoro-D-alanine and 2-deuterio analog, antibacterials related to the bacterial cell wallJournal of the American Chemical Society, 1976
- Inhibition studies of the enantiomers of β chloroalanine on purified Alanine Racemase from B.subtilisBiochemical and Biophysical Research Communications, 1976
- Reconstitution of D-amino acid aminotransferaseFEBS Letters, 1975
- Purification and crystallization of D-amino acid aminotransferase ofBacillus sphaericusFEBS Letters, 1974