Biochemical observations on the cartilage of achondroplastic (can) mice

Abstract
The achondroplastic can/can embryo can be distinguished from normal litter-mates at 17 days by reduced protein synthesis. After 3 days post partum protein synthesis is increased to levels well above normal, as is incorporation of glucose into mucopolysaccharides and the levels of uridine diphosphoglucose dehydrogenase and UDP-glucose-4-epimerase.