Suppressive Effects of Eugenol and Ginger Oil on Arthritic Rats
- 1 January 1994
- journal article
- research article
- Published by S. Karger AG in Pharmacology
- Vol. 49 (5) , 314-318
- https://doi.org/10.1159/000139248
Abstract
This study examined the effect of eugenol and ginger oil on severe chronic adjuvant arthritis in rats. Severe arthritis was induced in the right knee and right paw of male Sprague-Daw-ley rats by injecting 0.05 ml of a fine suspension of dead Mycobacterium tuberculosis bacilli in liquid paraffin (5 mg/ml). Eugenol (33 mg/kg) and ginger oil (33 mg/kg), given orally for 26 days, caused a significant suppression of both paw and joint swelling. These findings suggest that eugenol and ginger oil have potent antiinflammatory and/or antirheumatic properties.Keywords
This publication has 0 references indexed in Scilit: