TREATMENT OF INCAPACITATED EUTHYROID CARDIAC PATIENTS WITH RADIOACTIVE IODINE

Abstract
Evaluation of a new therapeutic method is difficult, particularly when the clinical course of the disease being treated is often irregular and occasionally characterized by unexpected remission and improvement. We have previously reported our earlier experience in treating a group of euthyroid cardiac patients by inducing hypothyroidism with radioactive iodine (I131)1; all patients had shown evidence of continued incapacity despite having received all standard forms of therapy. We felt that ultimate evaluation of this therapeutic measure would be furthered by the results of independent studies in various clinics; a questionnaire has been distributed, therefore, to clinics using radioactive iodine, and the results of I131treatment of euthyroid patients with advanced cardiac disease have been accumulated and analyzed. The entire group consists of 1,070 patients, 87 of our own series and 983 reported through the cooperation of 49 other clinics. We believe that for most patients with angina

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