Amide analogues of TSA: synthesis, binding mode analysis and HDAC inhibition
- 26 April 2003
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 13 (11) , 1861-1864
- https://doi.org/10.1016/s0960-894x(03)00284-1
Abstract
No abstract availableKeywords
This publication has 16 references indexed in Scilit:
- Major Phase I Biotransformation Pathways of Trichostatin A in Rat Hepatocytes and in Rat and Human Liver MicrosomesDrug Metabolism and Disposition, 2002
- Structurally Simple Trichostatin A-Like Straight Chain Hydroxamates as Potent Histone Deacetylase InhibitorsJournal of Medicinal Chemistry, 2002
- Inhibitors of Human Histone Deacetylase: Synthesis and Enzyme and Cellular Activity of Straight Chain HydroxamatesJournal of Medicinal Chemistry, 2002
- Histone Deacetylase: A Target for Antiproliferative and Antiprotozoal AgentsCurrent Medicinal Chemistry, 2001
- Development of Cytodifferentiating Agents for Cancer ChemotherapyHelvetica Chimica Acta, 2000
- Amide Analogues of Trichostatin A as Inhibitors of Histone Deacetylase and Inducers of Terminal Cell DifferentiationJournal of Medicinal Chemistry, 1999
- A Useful Procedure for the Preparation of (E,E)-2,4-Dienoates: Lithium Hydroxide-Promoted Dienylation by 4-PhosphonocrotonateThe Journal of Organic Chemistry, 1998
- A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylasesProceedings of the National Academy of Sciences, 1998
- Structural specificity for biological activity of trichostatin a, a specific inhibitor of mammalian cell cycle with potent differentiation-inducing activity in friend leukemia cells.The Journal of Antibiotics, 1990
- An Efficient Synthesis of Optically Active α-(t-Butoxycarbonylamino)-aldehydes from α-Amino AcidsSynthesis, 1983