Serum Transaminase Levels in Experimental Pericardial Injury.

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Abstract
Acute pericarditis was experimentally produced in dogs using sand, talc and cultures of alpha streptococci. Peak levels of serum glutamic oxalacetic transaminase ranged from normal to markedly elevated and were proportional to the severity of sub-epicardial myocardial injury rather than to the severity of pericardial injury. It is concluded that serum glutamic oxalacetic transaminase levels help to differentiate acute pericarditis from acute myocardial infarction only when the levels remain normal.