Portal hypertension secondary to azathioprine in myasthenia gravis
Open Access
- 1 December 1988
- journal article
- case report
- Published by Oxford University Press (OUP)
- Vol. 64 (758) , 950-952
- https://doi.org/10.1136/pgmj.64.758.950
Abstract
Summary: A 52 year old man with myasthenia gravis and normal liver function was treated with neostigmine, prednisolone and azathioprine. Three years after starting azathioprine he developed clinical evidence of portal hypertension. A liver biopsy showed nodular regenerative hyperplasia (NRH). The development of NRH following azathioprine treatment in a patient with myasthenia gravis strengthens the case for a causal role of azathioprine in producing NRH and portal hypertension.Keywords
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