Effect of High Phosphorus Intake on Calcium and Phosphorus Metabolism in Man

Publisher Website
Google Scholar
Abstract
The metabolic effects of phosphate added as glycerophosphate to the low and high calcium diet were studied in man under controlled dietary conditions. The increase in net absorption of phosphorus, upon addition of glycerophosphate, was greater during low calcium intake than during high calcium intake. Nevertheless, the improvement in phosphorus balance was similar during both intake levels of calcium since the urinary phosphorus excretion was higher during low calcium intake and the fecal phosphorus excretion was higher during high calcium intake. The high phosphorus intake led to a slight decrease in urinary calcium and to minor changes in fecal calcium excretion during both low and high calcium intake. The changes in calcium balance were only minor during the addition of phosphate to the low and high calcium diet, the calcium balances improving slightly during low calcium intake and remaining in the same range during high calcium intake. The simultaneous use of added amounts of calcium and of phosphate did not depress the intestinal absorption of either ion under the conditions of this study.