A Review of Protease Inhibitor‐Induced Hyperglycemia
- 2 January 1999
- journal article
- review article
- Published by Wiley in Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy
- Vol. 19 (1) , 114-117
- https://doi.org/10.1592/phco.19.1.114.30514
Abstract
Hyperglycemia is an adverse effect that occurs with all protease inhibitors, although few cases have been reported in the literature. Most patients with human immunodeficiency virus infection receiving antiretroviral therapy are also taking at least one protease inhibitor. Patients with a family history of diabetes mellitus may be at a greater risk of developing this adverse effect. It is therefore prudent to monitor all patients starting protease inhibitor therapy for the onset of diabetes or hyperglycemia, particularly those with a family history of diabetes. Baseline fasting plasma glucose or serum glucose level should be measured with follow‐up measurements every 3 months for approximately 6–12 months.Keywords
This publication has 10 references indexed in Scilit:
- Update: Clinically Significant Cytochrome P‐450 Drug InteractionsPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1998
- Severe Hyperglycemia in an HIV Clinic: Preexisting Versus Drug-Associated Diabetes MellitusJAIDS Journal of Acquired Immune Deficiency Syndromes, 1998
- New-Onset Diabetes Mellitus Associated with Use of Protease InhibitorAnnals of Internal Medicine, 1997
- Severe Diabetes Associated with Protease Inhibitor TherapyAnnals of Internal Medicine, 1997
- Protease inhibitor-associated hyperglycaemiaThe Lancet, 1997
- From the Food and Drug AdministrationPublished by American Medical Association (AMA) ,1997
- Antiretroviral Therapy for HIV Infection in 1997JAMA, 1997
- Antiretroviral therapy for HIV infection in 1997. Updated recommendations of the International AIDS Society-USA panelPublished by American Medical Association (AMA) ,1997
- Drug-Induced Disorders of Glucose ToleranceAnnals of Internal Medicine, 1993