Validation of Fiber-Optic Doppler Anemometry (FODA) for Characterizing the Droplet Size of Emulsions
- 1 January 1987
- journal article
- research article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 04 (4) , 301-304
- https://doi.org/10.1023/a:1016441119232
Abstract
Fiber-optic Doppler anemometry (FODA) is a useful tool to characterize polydisperse systems such as emulsions. The mean droplet radius of a model emulsion determined by FODA matched the mean radius determined by sizing droplets from a freeze-fractured freeze-etched scanning electron photomicrograph. The mean droplet radius determined by the Coulter technique was four times too large because the small droplets were not detected. The utility of FODA was further illustrated by its ability to accurately size droplets and monitor the coalescence upon aging of an intravenous lipid emulsion.This publication has 1 reference indexed in Scilit:
- A Study of Intravenous Emulsion Compatibility: Effects of Dextrose, Amino Acids, and Selected ElectrolytesDrug Intelligence & Clinical Pharmacy, 1981