The synthesis of 5-hydroxy chromenes
- 1 October 1985
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 63 (10) , 2589-2596
- https://doi.org/10.1139/v85-430
Abstract
The synthesis of 2,2-dimethyl-5-hydroxychromene (1d) is described. The synthesis of the analogous 5,7-dihydroxy derivatives, using similar conditions, yields the adduct 9 derived via a Bucherer type reaction. X-ray analysis of 9 demonstrated that a pyrrolidine group was in the 7-position, and that the 5-hydroxyl group was involved in a strong intramolecular hydrogen bond to the 4-keto oxygen atom.This publication has 2 references indexed in Scilit:
- Synthesis ofβ-TubanolAgricultural and Biological Chemistry, 1961
- Synthesis ofβ-Tubanol MethyletherAgricultural and Biological Chemistry, 1961