Semi-remote production of Br-76 and preparation of high specific activity radiobrominated pharmaceuticals for PET studies
- 1 April 2004
- journal article
- Published by Walter de Gruyter GmbH in Radiochimica Acta
- Vol. 92 (4-6) , 291-295
- https://doi.org/10.1524/ract.92.4.291.35605
Abstract
The PET radionuclide 76Br (t1/2=16.2 h) can be easily produced utilizing the nuclear reaction As(3He,2n)76Br. We use high-purity arsenic targets and isolate radioactive bromide by chromic acid oxidation followed by simple distillation of [76Br] hydrogen bromide using a semi-remote apparatus. Use of reagents with little or no carrier bromine yields high specific activity radiobrominated pharmaceuticals prepared from the distilled [76Br] hydrogen bromide.Keywords
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