Experimental estimation of the effective unstirred water layer thickness in the human jejunum, and its importance in oral drug absorption
- 14 February 2000
- journal article
- Published by Elsevier
- Vol. 3 (5) , 247-253
- https://doi.org/10.1016/0928-0987(95)00027-b
Abstract
No abstract availableKeywords
This publication has 16 references indexed in Scilit:
- The Lack of Effect of Induced Net Fluid Absorption on thein vivoPermeability of Terbutaline in the Human JejunumJournal of Drug Targeting, 1995
- Gastrointestinal absorption mechanisms: a comparison between animal and human modelsEuropean Journal of Pharmaceutical Sciences, 1994
- Role of villous surface area in absorption science versus religionDigestive Diseases and Sciences, 1993
- A new diffusion chamber system for the determination of drug permeability coefficients across the human intestinal epithelium that are independent of the unstirred water layerBiochimica et Biophysica Acta (BBA) - Biomembranes, 1992
- Physiological measurements of luminal stirring in the dog and human small bowel.Journal of Clinical Investigation, 1990
- Determination of intrinsic membrane transport parameters from perfused intestine experiments: A boundary layer approach to estimating the aqueous and unbiased membrane permeabilitiesJournal of Theoretical Biology, 1988
- Use of carbon monoxide to measure luminal stirring in the rat gut.Journal of Clinical Investigation, 1984
- Analysis of models for determining intestinal wall permeabilitiesJournal of Pharmaceutical Sciences, 1980
- Unstirred layer and kinetics of electrogenic glucose absorption in the human jejunum in situGut, 1977
- Correlation of diffusion coefficients in dilute solutionsAIChE Journal, 1955