Granzyme B: a natural born killer
- 12 May 2003
- journal article
- review article
- Published by Wiley in Immunological Reviews
- Vol. 193 (1) , 31-38
- https://doi.org/10.1034/j.1600-065x.2003.00044.x
Abstract
Summary: A main pathway used by cytotoxic T lymphocytes (CTLs) and natural killer cells to eliminate pathogenic cells is via exocytosis of granule components in the direction of the target cell, del...Keywords
This publication has 57 references indexed in Scilit:
- Functional significance of the perforin/granzyme cell death pathwayNature Reviews Immunology, 2002
- Lymphocyte-Mediated CytotoxicityAnnual Review of Immunology, 2002
- The Mannose 6-Phosphate/Insulin-like Growth Factor II Receptor Is a Nanomolar Affinity Receptor for Glycosylated Human Leukemia Inhibitory FactorJournal of Biological Chemistry, 1998
- Cytotoxic T-cell-derived granzyme B activates the apoptotic protease ICE-LAP3Current Biology, 1996
- FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling ComplexCell, 1996
- Involvement of MACH, a Novel MORT1/FADD-Interacting Protease, in Fas/APO-1- and TNF Receptor–Induced Cell DeathCell, 1996
- Conversion of the substrate specificity of mouse proteinase granzyme BNature Structural & Molecular Biology, 1994
- The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzymeCell, 1993
- A natural killer cell granule protein that induces DNA fragmentation and apoptosis.The Journal of Experimental Medicine, 1992
- The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell deathDevelopmental Biology, 1990