Multiple effects of α‐toxins on the nicotinic acetylcholine receptor
- 30 November 1987
- journal article
- Published by Wiley in FEBS Letters
- Vol. 224 (2) , 277-282
- https://doi.org/10.1016/0014-5793(87)80469-6
Abstract
Very low concentrations (5 nM) of α-toxin from the venom of Naja naja atra produced a characteristic fade in muscle compound action potential and tetanus induced by repetitive nerve stimulation which was identical to the effects of curare. High concentrations of α-toxin and all concentrations of α-bungarotoxin reduced the response but produced very little fade in comparison to curare. These results suggest that α-toxins have more than one effect at the neuromuscular junction.Keywords
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