Influence of Dietary Protein Level on Plasma Cholesterol Turnover and Fecal Steroid Excretion in the Chick

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Abstract
The turnover rate of plasma cholesterol in chicks fed 30% or 15% protein diets was investigated by administering cholesterol-4-14C and periodically determining the specific activity of plasma cholesterol. Fecal steroid excretion was also determined. The results indicate that the turnover rate of plasma cholesterol is higher in chicks fed a high protein diet compared with those fed a low protein diet. It is concluded that the hypocholesterolemic effect of dietary protein is mediated in part through a more rapid removal of cholesterol from the blood and excretion in the feces as cholesterol and bile acids.