The Charcot‐Marie‐Tooth syndrome: perceptions of disability and projected use of DNA diagnostic tests

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Abstract
The Charcot‐Marie‐Tooth group of disorders cause significant morbidity in a proportion of the individuals affected. We have shown that there is a significant correlation between the objective neurological assessment of their dysfunction and the individual's subjective perception of their disability. We have also documented the observation that individuals expressing an intention to use prenatal DNA diagnostic services and terminate an “affected” fetus are more severely affected by their disorder than those who would not, or who were unsure about their use of molecular genetic testing.