A MODEL SYSTEM FOR DETERMINING HISTOCOMPATIBILITY IN MAN*
Open Access
- 1 September 1963
- journal article
- research article
- Published by American Society for Clinical Investigation in Journal of Clinical Investigation
- Vol. 42 (9) , 1497-1503
- https://doi.org/10.1172/jci104834
Abstract
A model system for studying histocompatibility in man has been presented, which utilizes active immunization of an indifferent recipient as a means of evaluating the number of antigens shared by a prospective donor-recipient pair. This system is designed to detect subtle genetic compatibility between two individuals that would certainly be missed if cross-grafting alone were carried out. The practical utilization of such a system in the field of human homotransplantation has been presented.Keywords
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