Observations on the Antibody Content of the Blood in Patients with Multiple Myeloma

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Abstract
GREAT advances have been made in knowledge and understanding of the complex factors concerned in resistance or susceptibility to infection, but much remains that is controversial or incompletely understood.The current widespread interest in and demonstrated value of gamma-globulin administration in the prophylaxis of certain infectious diseases, such as viral hepatitis, has served to call attention to this constituent of the plasma proteins and its role in protection against infection. The recognition in recent years of that rare disorder, agammaglobulinemia, and the greatly increased susceptibility to infections in such patients, has also stimulated interest in gamma globulin and its ability . . .