The stereochemistry of phytoene biosynthesis

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Abstract
Experiments with carrot root preparations have demonstrated that all the eliminations of hydrogen at C-4 of mevalonic acid during its conversion into phytoene have the same stereospecificity; the 4-R hydrogen is retained and the 4S hydrogen is eliminated. The same stereospecific elimination is also involved in squalene formation in carrot slices.

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