Retroviruses and multiple sclerosis. I.
- 1 August 1990
- journal article
- research article
- Published by Wolters Kluwer Health in Neurology
- Vol. 40 (8) , 1251
- https://doi.org/10.1212/wnl.40.8.1251
Abstract
We were unable to identify an antibody to either HTLV-I or HIV-1 in patients with multiple sclerosis (MS) by ELISA, by radioimmune assay, or by radioimmune precipitation techniques. Immunoblot studies for HTLV-I-specific antibodies revealed faintly reactive bands in 2 of 44 MS patients but not in patients with other neurologic diseases. We did not find seroreactivity to HIV-1 or to the distantly related retrovirus, caprine arthritis encephalitis virus (CAEV). These findings suggest that MS is not related to infection by human retroviruses with antigenic similarity to HTLV-I, HIV-1, or CAEV.This publication has 5 references indexed in Scilit:
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