Biosynthesis of [6]-gingerol, pungent principle of Zingiber officinale

1 January 1976

journal article
research article
Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications

No. 18,p. 711-712
https://doi.org/10.1039/c39760000711

Abstract

Evidence is adduced for a scheme of bio-synthesis for (S)-(+)-[6]-gingerol in Zingiber officinale Roscoe, in which dihydroferulate is built up from phenylalanine and participates in a new example of a ‘biological Claisen reaction’ with malonate and hexanoate; the β-diketone product is then reduced to [6]-gingerol.