Crystallization of pertussigen from Bordetella pertussis
- 1 January 1981
- journal article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 31 (1) , 495-499
- https://doi.org/10.1128/iai.31.1.495-499.1981
Abstract
A method is described for crystallizing pertussigen from Bordetella pertussis. The crystalline material induced histamine hypersensitivity in mice at a dose of 0.5 ng of protein and leukocytosis at a dose of 100 ng and was toxic at a dose of 429 microgram. The histamine-sensitizing activity and the toxicity were as high as ever reported.Keywords
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