Clinical Trials with Fenbendazole and Oxibendazole for Strongyloides westeri Infection in Foals

Abstract
SUMMARY: In 2 trials, treatment with fenbendazole (50 mg/kg of body weight by stomach tube) resulted in reductions of Strongyloides westeri worm egg counts by averages of 86% and > 99%, respectively, and in complete clearance of eggs from feces of 9 of 12 foals that were positive before treatment. In 6 trials, treatment with oxibendazole (10 mg/kg of body weight intraorally) resulted in 100% reduction of strongyloides worm egg counts in 5 trials and 81% in 1 trial; clearance of S westeri eggs from feces was recorded for 31 of 33 foals that were positive before treatment.