Fatal Anaphylactic Shock

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Abstract
For more than 35 years, the medical literature has contained numerous publications concerning (1) the prevention of the 50% fatal disease tetanus, by either active or passive immunization, and (2) the dangers and severe reactions resulting from the use of horse serum in the passive type of prevention. The following case, however, is the first report of a death occurring as the direct result of an intracutaneous skin test of a dilute dose of tetanus antitoxin obtained from horse serum. Case Report A 59-year-old man was seen in the office with the complaint of a puncture wound of the right palm, made with a knife, the cleanliness of which was questionable. The patient did not know of ever having had an injection of horse serum or tetanus antitoxin previously. He had never had toxoid injections, to his knowledge. His only allergic history was that he had had hives once following

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