Abstract
In this issue of Human Reproduction we publish two papers on the cost-effectiveness of gonadotrophin therapies within IVF in the UK (Daya et al., 2001; Sykes et al., 2001). Cost-effectiveness issues are essentially a parochial activity since costing aspects are inevitably different in different health care systems, but although the detailed outcome of such an analysis is restricted to practice in one country, there are often insights of wider application as a result of the analysis and the methods used.