Training, drive level, and drug effects: A temporal analysis of their combined influence of behavior.
- 1 February 1963
- journal article
- Published by American Psychological Association (APA) in Journal of Comparative and Physiological Psychology
- Vol. 56 (1) , 183-189
- https://doi.org/10.1037/h0048747
Abstract
Effects of these variables on 4 time measures describing the essential or relevant components of a water-reinforced lever-pressing response, as well as on the time spent in irrelevant activities (grooming, sniffing, and sitting) were studied in 44 rats. Chlorpromazine decreased response rate at the 2 higher levels of training but not at the lowest level; methylphenidate decreased rate at the 2 lower drive levels but not a the highest. The response decrements were associated with a decrease in the speed of the relevant components in the case of chlorpromazine, and with an increase in time spent in irrelevant activities in the case of methylphenidate. A tentative generalization about the basis of differential effects of stimulant and depressant drugs on behavior is suggested. (PsycINFO Database Record (c) 2006 APA, all rights reserved)Keywords
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