Frequency of tw Alleles in a Confined Population of Wild House Mice.

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Abstract
A sample (R - 3) from a confined population of mice, consisting of 70 males and 68 females was tested for the presence of t w alleles. This population is descended from animals caught in the wild. Of 44 tested males 50% were +/tW; while of 55 tested females, 65% contained tw. This population has an overall-frequency of 58% t W containing fertile individuals. The present generation of this population seems to contain only t W2, a viable allele, and +. Previously tested generations (R - 1 and R - 2) had contained both t w2 and tw1. The latter is a lethal allele. The +/t w2 males of this population transmitted t w2 gametes to their offspring in excessive numbers, a phenomenon known from other studies and referred to as "segregation ratio abnormality." Discussed is the overall high frequency of t W-containing individuals found in this population as compared with animals caught in the wild. Also discussed is the disparity between males and females with respect to frequencies of sterility and t W-containing individuals.
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