Fragment-based screening using X-ray crystallography and NMR spectroscopy
- 1 October 2007
- journal article
- review article
- Published by Elsevier in Current Opinion in Chemical Biology
- Vol. 11 (5) , 485-493
- https://doi.org/10.1016/j.cbpa.2007.07.010
Abstract
No abstract availableKeywords
This publication has 60 references indexed in Scilit:
- Assessment of automatic ligand building inARP/wARPActa Crystallographica Section D-Biological Crystallography, 2006
- FAST-NMR: Functional Annotation Screening Technology Using NMR SpectroscopyJournal of the American Chemical Society, 2006
- Using Fragment Cocktail Crystallography To Assist Inhibitor Design of Trypanosoma brucei Nucleoside 2-DeoxyribosyltransferaseJournal of Medicinal Chemistry, 2006
- Screening in a spirit haunted worldDrug Discovery Today, 2006
- The INPHARMA Method: Protein‐Mediated Interligand NOEs for Pharmacophore MappingAngewandte Chemie International Edition in English, 2005
- Crystal Structures of Proto-oncogene Kinase Pim1: A Target of Aberrant Somatic Hypermutations in Diffuse Large Cell LymphomaJournal of Molecular Biology, 2005
- SOS-NMR: A Saturation Transfer NMR-Based Method for Determining the Structures of Protein−Ligand ComplexesJournal of the American Chemical Society, 2004
- Fluorine-NMR Experiments for High-Throughput Screening: Theoretical Aspects, Practical Considerations, and Range of ApplicabilityJournal of the American Chemical Society, 2003
- NMR-Based Screening of Proteins Containing 13C-Labeled Methyl GroupsJournal of the American Chemical Society, 2000
- Development and validation of a genetic algorithm for flexible docking 1 1Edited by F. E. CohenJournal of Molecular Biology, 1997