CLOSING VOLUME AND FLOW VOLUME ABNORMALITIES IN ALPHA-ANTITRYPSIN PHENOTYPE GROUPS IN A COMMUNITY POPULATION
- 1 January 1978
- journal article
- research article
- Published by Elsevier
- Vol. 117 (1) , 179-181
- https://doi.org/10.1164/arrd.1978.117.1.179
Abstract
Alpha1-antitrypsin phenotype [Pi] groups, found in a community population studied in Tucson [Arizona, USA] were compared by using the maximum expiratory flow volume curve and the single-breath N test, alone and in combination. Subjects 25-54 yr of age were used for the comparison, among whom there were 728 Pi M, 29 Pi MZ and 62 Pi MS phenotypes. None of the flow volume parameters or closing volume parameters was able to differentiate among phenotype groups; subjects in groups heterozygous for alpha1-antitrypsin did not differ from individuals homozygous for Pi M with regard to any or all flow volume or closing volume parameters.This publication has 5 references indexed in Scilit:
- Relation of Protease Inhibitor Phenotypes to Obstructive Lung Diseases in a CommunityNew England Journal of Medicine, 1977
- CLOSING VOLUME TEST - EVALUATION OF NITROGEN AND BOLUS METHODS IN A RANDOM POPULATIONPublished by Elsevier ,1977
- CLINICAL, EPIDEMIOLOGIC, AND PULMONARY-FUNCTION STUDIES IN ALPHA-1-ANTITRYPSIN-DEFICIENT SUBJECTS OF PI Z-TYPEPublished by Elsevier ,1976
- MAXIMAL EXPIRATORY FLOW-VOLUME CURVE - ITS USE IN DETECTION OF VENTILATORY ABNORMALITIES IN A POPULATION STUDYPublished by Elsevier ,1976
- MAXIMAL EXPIRATORY FLOW-VOLUME CURVE - NORMAL STANDARDS, VARIABILITY, AND EFFECTS OF AGEPublished by Elsevier ,1976