B Lymphocyte Alloantigen Specificities Present on Cultured Lymphoblastoid Cell Lines
Open Access
- 1 October 1976
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 117 (4) , 1300-1302
- https://doi.org/10.4049/jimmunol.117.4.1300
Abstract
Thirty-three of 34 cultured human lymphoblastoid B cell lines have been shown to express four out of five polymorphic non-HLA specificities expressed by normal B lymphocytes. The specificities were detected by 32 alloantisera produced by absorption with pooled platelets to remove HLA activity and selected from over 400 pregnancy sera. One B group (B2) which was expressed by 23% of a panel of normal B lymphocytes was not found on any of the cultured lines tested. Four T cell lines tested and myeloid line (K562) did not react with any of the B cell alloantisera.This publication has 1 reference indexed in Scilit: