Long-Term Potentiation--A Decade of Progress?
- 17 September 1999
- journal article
- review article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 285 (5435) , 1870-1874
- https://doi.org/10.1126/science.285.5435.1870
Abstract
Long-term potentiation of synaptic transmission in the hippocampus is the leading experimental model for the synaptic changes that may underlie learning and memory. This review presents a current understanding of the molecular mechanisms of this long-lasting increase in synaptic strength and describes a simple model that unifies much of the data that previously were viewed as contradictory.Keywords
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