Fever, Rash, and Myalgias of Disseminated Candidiasis During Antifungal Therapy

Abstract
• A patient with acute lymphocytic leukemia was seen initially with the signs of fever, rash, and myalgias that occurred sequentially despite antifungal therapy. Culture- and necropsy-proved Candida tropicalis infection was responsible. The appearance of myositis in a patient receiving adequate amphotericin B therapy for a sensitive C tropicalis infection suggests a poor prognosis. (Arch Intern Med 1981;141:1233)