Lymphocytes Forming Rosettes with Sheep Erythrocytes in Metastatic Pleural Effusions2

1 May 1976

journal article
research article
Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute

Vol. 56 (5) , 1051-1052
https://doi.org/10.1093/jnci/56.5.1051

Abstract

Percentages of lymphocytes forming rosettes with sheep erythrocytes at 29° C were determined in 10 cancer patients with metastases to the pleural cavity. Compared with normal controls, the patients showed a decreased proportion of rosette-forming cells (RFC) in the peripheral blood. The same patients had elevated levels of RFC in their metastatic pleural effusions. However, 2 patients with benign diseases had normal levels of RFC in their peripheral blood and pleural transudates. These observations suggested that in cancer patients some T-cells might migrate from the peripheral blood and accumulate in sites of tumor infiltration such as the pleural cavity.

Keywords

This publication has 1 reference indexed in Scilit:

Diagnostic Significance of Lymphocytes in Pleural Effusions
Annals of Internal Medicine, 1967