d-lysergic acid-activating enzyme from the ergot fungus Claviceps purpurea
- 15 March 1984
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 218 (3) , 857-862
- https://doi.org/10.1042/bj2180857
Abstract
A D-lysergic acid-activating enzyme from the ergot fungus Claviceps purpurea was purified about 145-fold. The enzyme was able to catalyse both the D-lysergic acid-dependent ATP-pyrophosphate exchange and the formation of ATP from D-lysergic acid adenylate and pyrophosphate. Both reactions were also catalysed to a decreased but significant extent with respect to dihydrolysergic acid. The molecular mass of the enzyme was estimated to lie between 135 and 140 kDa. The involvement of the enzyme in the biosynthesis of ergot peptide alkaloids is discussed.This publication has 12 references indexed in Scilit:
- The Chemical Synthesis of Amino Acyl AdenylatesPublished by Elsevier ,2021
- Antibiotic Polypeptides – Biosynthesis on Multifunctional Protein TemplatesPlanta Medica, 1979
- The determination of aminoacyl adenylate by thin-layer chromatographyAnalytical Biochemistry, 1977
- A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye BindingAnalytical Biochemistry, 1976
- BIOSYNTHESE DES PEPTIDTEILS DER MUTTERKORNALKALOIDE VOM CYCLOL–TYPPlanta Medica, 1975
- [45] Tyrocidine synthetase systemPublished by Elsevier ,1975
- [48] Kinetic techniques for the investigation of amino acid: tRNA ligases (aminoacyl-tRNA synthetases, amino acid activating enzymes)Published by Elsevier ,1974
- Attempts to Map a Process Evolution of Peptide BiosynthesisScience, 1971
- Ergotamine production in submerged culture and physiology of Calviceps purpurea.1967
- The Synthesis and Some Properties of Amino Acyl AdenylatesJournal of Biological Chemistry, 1959