Immunologic Aspects of 1,2-Dimethylhydrazine-Induced Colon Tumors in Rats2
- 1 May 1975
- journal article
- research article
- Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute
- Vol. 54 (5) , 1231-1235
- https://doi.org/10.1093/jnci/54.5.1231
Abstract
Investigation of immunologic aspects of colon tumors induced in rats by 1,2-dimethylhydrazine demonstrated that: 1) An antigen in an extract of colon tumors was not detected in the normal colon. It was related to antigens in rat fetuses and did not cross-react immunologically with carcinoembryonic antigen. 2) Mucinous adenocarcinomas of the colon were significantly associated spatially with lymphoid follicles.Keywords
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