Stable membrane potentials and mechanical K+ responses activated by internal Ca2+ in HeLa cells
- 1 February 1983
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Physiology and Pharmacology
- Vol. 61 (2) , 144-148
- https://doi.org/10.1139/y83-021
Abstract
Stable membrane potentials have been measured with microelectrodes in HeLa cells and their average value (−38 mV) compares well with the Cl− electrochemical potential (−34 mV). A hyperpolarizing response is observed upon microelectrode penetrations and following a mechanical or electrical shock; this response is due to a large increase in the K+ permeability, which can also be triggered by Ca2+ injection or blocked by EGTA injection through the microelectrode. Stable hyper-polarizations are obtained with the Ca2+ ionophore A 23187.This publication has 1 reference indexed in Scilit:
- Evidence for an intracellular calcium store releasable by surface stimuli ifibroblasts (L cells).The Journal of general physiology, 1979