Aphagia and adipsia produced by unilateral hypothalamic lesions in rats

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Abstract
Small unilateral lesions in the lateral hypothalamus produced up to 4.0 days of aphagia and 5.5 days of adipsia. After recovery, when the rats were eating and drinking normally again, the lesions were bilateralized by placing lesions contralateral to the original lesions. The results indicated that the relative durations of aphagia or adipsia produced by the initial unilateral lesions were a very reliable indication, on a more restricted scale, of the relative durations of aphagia or adipsia that would have been produced if the lesions had initially been bilateral.

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