An inactive cytochrome P450 CYP2D6 allele containing a deletion and a base substitution

This publication has 10 references indexed in Scilit:

• The cytochrome P450 CYP2D6 allelic variant CYP 2D6J and related polymorphisms in a European population
  Pharmacogenetics, 1994
• Evidence for a new variant CYP2D6 allele CYP2D6J in a Japanese population associated with lower in vivo rates of sparteine metabolism
  Pharmacogenetics, 1993
• Molecular basis of genetic variation in debrisoquin hydroxylation in Chinese subjects: Polymorphism in RFLP and DNA sequence of CYP2D6
  Clinical Pharmacology & Therapeutics, 1993
• Metabolic polymorphisms
  Pharmacology & Therapeutics, 1993
• Analysis of the CYP2D6 gene in relation to debrisoquin and desipramine hydroxylation in a Swedish population
  Clinical Pharmacology & Therapeutics, 1992
• Concordance of P450 2D6 (debrisoquine hydroxylase) phenotype and genotype: inability of dextromethorphan metabolic ratio to discriminate reliably heterozygous and homozygous extensive metabolizers.
  1991
• Debrisoquine/Sparteine Hydroxylation Genotype and Phenotype: Analysis of Common Mutations and Alleles ofCYP2D6in a European Population
  DNA and Cell Biology, 1991
• Genetic and metabolic criteria for the assignment of debrisoquine 4-hydroxylation (cytochrome P4502D6) phenotypes
  Pharmacogenetics, 1991
• Multiple mutations of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine. Study of the functional significance of individual mutations by expression of chimeric genes.
  Journal of Biological Chemistry, 1990
• THE HUMAN DEBRISOQUINE 4-HYDROXYLASE (CYP2D) LOCUS - SEQUENCE AND IDENTIFICATION OF THE POLYMORPHIC CYP2D6 GENE, A RELATED GENE, AND A PSEUDOGENE
  1989