Biometrical studies to detect new genes with major effects on quantitative risk factors for atherosclerosis

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Abstract
Previously unidentified genetic loci that have major effects on quantitative risk factors for atherosclerosis can be detected by statistical genetic analysis of patterns of phenotypic variation in families. Major loci have been detected that influence serum concentrations of lipoproteins and apolipoproteins. Further studies are needed to localize these genes and to determine their functions and their interactions with environmental and other genetic factors.
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