Convenient Asymmetric Synthesis of (1R,3R)-(+)- and (1S,3S)-(-)-1,3-Diphenylpropane-1,3-diols

Abstract
Kinetic resolution via a Sharpless epoxidation serves as the key step to provide the useful C2 chiral auxiliaries (R,R)- and (S,S)-1,3-diphenylpropane-1,3-diols, in good yield and high enantiomeric purity from the commercially available 1,3-diphenylprop-1-en-3-one.

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