Cadherin-13, a Mediator of Calcium-Dependent Cell-Cell Adhesion, Is Silenced by Methylation in Chronic Myeloid Leukemia and Correlates With Pretreatment Risk Profile and Cytogenetic Response to Interferon Alfa
- 15 April 2003
- journal article
- hematologic malignancies
- Published by American Society of Clinical Oncology (ASCO) in Journal of Clinical Oncology
- Vol. 21 (8) , 1472-1479
- https://doi.org/10.1200/jco.2003.08.166
Abstract
Purpose: Cadherin-13 (CDH13) is a newly characterized cadherin molecule responsible for selective cell recognition and adhesion, the expression of which is decreased by methylation in a variety of ...Keywords
This publication has 39 references indexed in Scilit:
- BCR-ABL–induced adhesion defects are tyrosine kinase–independentBlood, 2002
- The cadherin-catenin adhesion system in signaling and cancerJournal of Clinical Investigation, 2002
- The molecular biology of chronic myeloid leukemiaBlood, 2000
- DNA MethylationBlood, 1999
- p27 is involved in N-cadherin-mediated contact inhibition of cell growth and S-phase entryOncogene, 1999
- H–cadherin, a novel cadherin with growth inhibitory functions and diminished expression in human breast cancerNature Medicine, 1996
- Inhibition of apoptosis by BCR-ABL in chronic myeloid leukemiaBlood, 1994
- Mechanisms underlying abnormal trafficking of malignant progenitors in chronic myelogenous leukemia. Decreased adhesion to stroma and fibronectin but increased adhesion to the basement membrane components laminin and collagen type IV.Journal of Clinical Investigation, 1992
- Cadherin Cell Adhesion Receptors as a Morphogenetic RegulatorScience, 1991
- Altered adhesive interactions with marrow stroma of haematopoietic progenitor cells in chronic myeloid leukaemiaNature, 1987