Membrane response to 1-methyladenine requires the presence of the nucleus
- 1 November 1979
- journal article
- letter
- Published by Springer Nature in Nature
- Vol. 282 (5734) , 89-90
- https://doi.org/10.1038/282089a0
Abstract
Meiosis is re-initiated in starfish oocytes by the action of the hormone 1-methyladenine (1-MA)1. It is thought that the primary trigger is localised at the plasma membrane2,3, and early changes reported are the activation of a Na+ pump4 and variation in membrane potential and conductance5,6. We report here that external application of 1-MA results in an irreversible switching of the starfish oocyte membrane from one stable electrical state to another. This induced change requires the presence of the germinal vesicle.Keywords
This publication has 9 references indexed in Scilit:
- Membrane noise and conductance increase during single spermatozoon—egg interactionsNature, 1978
- Hormonal control of meiosis reinitiation in starfish oocytesExperimental Cell Research, 1978
- An electrophysiological study of the membrane properties of the immature and mature oocyte of the Batstar, Patiria miniataDevelopmental Biology, 1976
- Site of action of 1-methyladenine in inducing oocyte maturation in starfish: Kinetic evidence for receptors localized on the cell membraneExperimental Cell Research, 1975
- Potassium rectifications of the starfish oocyte membrane and their changes during oocyte maturation.The Journal of Physiology, 1975
- Site of action of 1-methyladenine in inducing oocyte maturation in starfishExperimental Cell Research, 1970
- MECHANISM OF STARFISH SPAWNING. II. SOME ASPECTS OF ACTION OF A NEURAL SUBSTANCE OBTAINED FROM RADIAL NERVEThe Biological Bulletin, 1969
- Membrane permeability changes in amphibian eggs at ovulationJournal of Cellular Physiology, 1966
- Electrical Characteristics and Activation Potential of Bufo EggsThe Journal of general physiology, 1959