Surgical Management of Neonatal Jaundice
- 14 June 1973
- journal article
- review article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 288 (24) , 1284-1286
- https://doi.org/10.1056/nejm197306142882407
Abstract
PERSISTENT obstructive jaundice in infants presents a diagnostic and therapeutic challenge. Several forms of biliary-duct obstruction, such as biliary atresia, choledochal cyst or inspissated bile syndrome, require surgical repair. Almost 1/2 of all infants with prolonged jaundice have cholestasis of nonsurgical origin. Cholestasis developing in the first few months of life may be caused by neonatal hepatitis, intrahepatic biliary atresia, toxoplasmosis, cytomegalic inclusion disease, rubella, herpes simplex, coxsackie virus, syphilis and metabolic diseases such as galactosemia. Neonatal hepatitis accounts for 85 to 90 per cent of the nonsurgical types of jaundice.The causes of neonatal hepatitis and biliary atresia are . . .Keywords
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