Lanthanide Complexes Coordinated by N‐Substituted (R)‐1,1′‐Binaphthyl‐2,2′‐diamido Ligands in the Catalysis of Enantioselective Intramolecular Hydroamination

Abstract
A new family of lanthanide ionic complexes derived from chiral, substituted (R)-binaphthylamine ligands, [Li(thf)4][Ln{(R)-C20H12(NR)2}2] (Ln=Yb, Sm, Nd, or Lu), has been synthesized and characterized by X-ray crystal structure analyses. All complexes have been tested as new catalysts for the hydroamination/cyclization of 1-(aminomethyl)-1-allylcyclohexane. Ytterbium complexes proved to be both the most active and the most enantioselective, and the use of the complex [Li(thf)4][Yb{(R)-C20H12(NC3H7)2}2], bearing isopropyl radicals on the nitrogen atoms, allowed the formation of the corresponding spiropyrrolidine in high yield with up to 70 % ee.

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