A Mouthrinse which Optimizes in vivo Generation of Hypothiocyanite
- 1 October 1983
- journal article
- research article
- Published by SAGE Publications in Journal of Dental Research
- Vol. 62 (10) , 1062-1066
- https://doi.org/10.1177/00220345830620101101
Abstract
We report here the properties of a mouthrinse which enhances one of the natural defense factors in human saliva, the salivary peroxidase system. Concentrations of the antimicrobial agent, the hypothiocyanite (OSCN-) ion, can be increased in vivo to bacteriostatic levels by use of a mouthrinse which is 4 mM (0.014%) in hydrogen peroxide and I mM (0.0097%) in potassium thiocyanate at pH 5.5. The volume of the rinse, the H2O2 concentrations, and the pH were shown to be determinants of the concentration of OSCN- generated by the rinse.This publication has 18 references indexed in Scilit:
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