DNA-binding Proteins in the Nuclei of Herpes Simplex Virus-infected, Arginine-deprived, BSC-1 Cells

Abstract
Nine proteins accumulate in nuclei of arginine-deprived herpes simplex virus-infected [African Green monkey kidney BSC-1] cells. Of these, 8 bound to double-stranded DNA-cellulose and eluted with 0.3 and 0.6 M KCl, while one of 160,000 MW had no affinity for the DNA. Five of the DNA-binding proteins were identified as virus enzymes: 2 were DNA polymerases, 2 were alkaline DNases and 1 was the thymidine kinase.